Serum creatinine concentration

In ethylene glycol poisoning, a raised serum creatinine concentration indicates acute kidney injury and is associated with reduced ethylene glycol elimination and a worse prognosis.

In methanol poisoning due to ingestion of model aeroplane fuel or rocket fuel, some older laboratory creatinine assays can report falsely raised serum creatinine concentrations. This occurs due to the presence of nitromethane in the fuels and is not indicative of acute kidney injury. Nitromethane does not affect enzymatic creatinine assays on point-of-care blood gas analysis.