Key investigations

Key investigations for clozapine poisoning are:

  • electrocardiogram (ECG)
  • full blood count in patients on long-term clozapine—measure leucocyte and granulocyte counts at presentation
  • bedside bladder volumetric ultrasound scan every 4 hours—to detect urinary retention.

Serum clozapine concentration is not used for managing an acute ingestion.