Seizure control

In beta-blocker poisoning, intracellular glucose depletion can occur despite a normal blood glucose concentration. If the patient has a seizure, treat presumptively with intravenous glucose.

For adults, use:

1 glucose 50% 50 mL intravenously, by slow injection, preferably via a central venous catheter or a large peripheral vein, every 30 to 60 minutes if required for seizures beta-blocker poisoning - seizure control

OR

1 glucose 10% 250 mL intravenously, by slow injection, via a large peripheral vein, every 30 to 60 minutes if required for seizures. beta-blocker poisoning - seizure control

For children, use:

glucose 10% 2.5 mL/kg intravenously, by slow injection, via a large peripheral vein, every 30 to 60 minutes if required for seizures.

If seizures are persistent or recurrent, treat with an intravenous benzodiazepine.