Corticosteroid therapy

Corticosteroids are often recommended for caustic ingestions to reduce the risk of developing late oesophageal strictures; however, evidence is largely limited to animal studies. A 2014 study in children with documented oesophageal injury suggested high-dose intravenous methylprednisolone (1 g/1.73 m2 daily for 3 days) may reduce oesophageal stricture formation from 30% to 11%1.

Consult a gastroenterologist regarding whether to use corticosteroids. Routine use of corticosteroids may increase the risk of oesophageal perforation after severe oesophageal injury.

1 Usta M, Erkan T, Cokugras FC, Urganci N, Onal Z, Gulcan M, et al. High doses of methylprednisolone in the management of caustic esophageal burns. Pediatrics 2014;133(6):E1518–24. [URL]Return