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Antibiotic
Prevention of infection
Primary prophylaxis in immunocompromised adults without HIV infection
Pneumocystis jirovecii pneumonia prophylaxis in immunocompromised adults without HIV infection
Antibiotic
Bartonella infections
Osteomyelitis
Septic arthritis of a native joint
Bone and joint infections other than osteomyelitis and native joint septic arthritis
Sepsis or septic shock associated with a bone or joint source
Directed therapy for native bone or joint infection
Brucellosis
Infective endocarditis
Cardiovascular system infections other than endocarditis
Central nervous system infections
Coronavirus disease 2019 (COVID-19)
Cryptococcosis
Cytomegalovirus (CMV) infection
Infectious diarrhoea
Ear, nose and throat infections
Eye infections
Febrile neutropenia
Genital and sexually transmissible infections
Human immunodeficiency virus
Intra-abdominal infections
Leptospirosis
Lyme disease
Mediastinitis
Melioidosis
Mpox (monkeypox)
Nocardiosis
Nontuberculous mycobacterial infections
Oesophageal infections
Parasitic infections
Perinatal infections
Prevention of infection
Principles of surgical antibiotic prophylaxis
Surgical antibiotic prophylaxis for specific procedures
Prevention of infective endocarditis
Clearance antibiotics for invasive meningococcal or Hib disease
Prevention of infection in patients with asplenia or hyposplenism
Postexposure prophylaxis against bloodborne viruses
Prevention of infection in patients with cirrhosis and upper gastrointestinal bleeding
Primary prophylaxis in immunocompromised adults without HIV infection
What is covered in this topic?
Interventions to prevent opportunistic infections in immunocompromised patients
Assessing the need for antimicrobial prophylaxis in immunocompromised adults without HIV infection
Pneumocystis jirovecii pneumonia prophylaxis in immunocompromised adults without HIV infection
Introduction
Preferred PJP prophylaxis
Alternative PJP prophylaxis
Toxoplasma gondii prophylaxis in immunocompromised adults without HIV infection
Cytomegalovirus prophylaxis in immunocompromised adults without HIV infection
Yeast and mould antifungal prophylaxis in immunocompromised adults without HIV infection
Herpes simplex virus and varicella-zoster virus prophylaxis in immunocompromised adults without HIV infection
Hepatitis B virus prophylaxis in immunocompromised adults without HIV infection
Mycobacterium tuberculosis prophylaxis in immunocompromised adults without HIV infection
Influenza virus prophylaxis in immunocompromised adults without HIV infection
Streptococcus pneumoniae prophylaxis in immunocompromised adults without HIV infection
Strongyloides stercoralis prophylaxis in immunocompromised adults without HIV infection
Burkholderia pseudomallei prophylaxis in immunocompromised adults without HIV infection
Neisseria meningitidis prophylaxis in adults treated with eculizumab
Progressive multifocal leukoencephalopathy (John Cunningham virus)
Further reading
References
Prevention of invasive group A streptococcal infection
Prophylaxis for medicinal leech therapy
Selective decontamination of the digestive tract in patients on invasive mechanical ventilation
Q fever
Pneumonia
Directed therapy for pneumonia
Respiratory tract infections other than pneumonia
Acute rheumatic fever
Rickettsial infections
Salivary gland infections
Sepsis and septic shock: Identification and initial management
Sepsis and septic shock: Empirical regimens
Directed therapy for bloodstream infections, including sepsis and septic shock
Skin and soft tissue infections
Traumatic wound infections
Urinary tract infections in adults
Urinary tract infections in children
Identifying resistant pathogens or Candida species
Principles of obtaining blood for culture
Principles of antimicrobial use
Antimicrobial stewardship (AMS)
Practical information on using antimicrobial drugs
Aminoglycoside use
Vancomycin use in adults
Vancomycin use in young infants and children
Monitoring antimicrobial blood concentrations
Ambulatory antimicrobial therapy
Antimicrobial hypersensitivity
Kidney impairment and antimicrobial dosing
Contact details for health departments and public health units
Amikacin initial dose calculator
Gentamicin initial dose calculator
Tobramycin initial dose calculator
Pneumocystis jirovecii pneumonia prophylaxis in immunocompromised adults without HIV infection
Introduction
Preferred PJP prophylaxis
Alternative PJP prophylaxis
