Treatment for serotonergic toxidrome

If a patient develops symptoms and signs of serotonergic toxidrome (neuromuscular excitation, hyperthermia and altered conscious state) due to co-ingestion of isoniazid with another serotonergic drug, see Treatment for serotonergic toxidrome for treatment recommendations. Management focuses on supportive care, gentle sedation, cooling, and sometimes antidotal therapy.