Follow-up for patients with Clostridioides difficile infection

Repeat microbiological testing for Clostridioides difficile is only indicated in symptomatic patients. Tests often remain positive for over a month, even after effective therapy, so repeat testing is not generally indicated within this time.

Advise patients that:

• recurrence of C. difficile infection is possible, particularly with subsequent courses of antibiotics
• repeat testing is not generally advised unless recurrent symptoms develop.