Overview of managing Clostridioides difficile infection

An overview of managing a new episode of diarrhoea suspected to be Clostridioides difficile infection is provided for adults and children younger than 18 years.

Figure 1. Overview of managing a new episode of diarrhoea in adults with risk factors for Clostridioides difficile infection
Introduction to Clostridioides difficile infectionAssessment of Clostridioides difficile infectionIdentifying sepsis or septic shock in adultsSevere, complicated or fulminant Clostridioides difficile infectionTreatment for the first episode of Clostridioides difficile infectionFirst recurrence of C. difficile infection in adultsSecond and subsequent recurrences of C. difficile infection in adults
Note:

FMT = faecal microbiota transplantation

Figure 2. Overview of managing a new episode of diarrhoea in children younger than 18 years with risk factors for Clostridioides difficile infection
Introduction to Clostridioides difficile infectionSeverity assessment of C. difficile infection in childrenAssessment of Clostridioides difficile infectionIdentifying sepsis and septic shockSevere, complicated or fulminant Clostridioides difficile infectionTreatment for the first episode of Clostridioides difficile infectionFirst recurrence of C. difficile infection in children younger than 18 years
Note:

NB1: For definitions of sepsis and septic shock in children, see Identifying sepsis or septic shock in neonates, infants and children.