Key references: Step 2 therapy for asthma in adults and adolescents

  • Bateman ED, Reddel HK, O’Byrne PM, Barnes PJ, Zhong N, Keen C, et al. As-needed budesonide-formoterol versus maintenance budesonide in mild asthma. N Engl J Med 2018;378(20):1877–87. https://www.ncbi.nlm.nih.gov/pubmed/29768147
  • Chauhan BF, Ducharme FM. Anti-leukotriene agents compared to inhaled corticosteroids in the management of recurrent and/or chronic asthma in adults and children. Cochrane Database Syst Rev 2012;(5):CD002314. https://www.ncbi.nlm.nih.gov/pubmed/22592685
  • Global Initiative for Asthma (GINA)Global strategy for asthma management and prevention: main report. Wisconsin: GINA; 2019. www.ginasthma.org
  • Joos S, Miksch A, Szecsenyi J, Wieseler B, Grouven U, Kaiser T, et al. Montelukast as add-on therapy to inhaled corticosteroids in the treatment of mild to moderate asthma: a systematic review. Thorax 2008;63(5):453–62. https://www.ncbi.nlm.nih.gov/pubmed/18443162
  • O’Byrne PM, FitzGerald JM, Bateman ED, Barnes PJ, Zhong N, Keen C, et al. Inhaled combined budesonide-formoterol as needed in mild asthma. N Engl J Med 2018;378(20):1865–76. https://www.ncbi.nlm.nih.gov/pubmed/29768149
  • Philip G, Nayak AS, Berger WE, Leynadier F, Vrijens F, Dass SB, et al. The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis. Curr Med Res Opin 2004;20(10):1549–58. https://www.ncbi.nlm.nih.gov/pubmed/15462688