Key references: Comorbidities and complications of COPD

Cardiovascular disease

• Dransfield MT, Voelker H, Bhatt SP, Brenner K, Casaburi R, Come CE, et al. Metoprolol for the prevention of acute exacerbations of COPD. N Engl J Med 2019. https://www.ncbi.nlm.nih.gov/pubmed/31633896
• Salpeter S, Ormiston T, Salpeter E. Cardioselective beta-blockers for chronic obstructive pulmonary disease. Cochrane Database Syst Rev 2005;(4):CD003566. https://www.ncbi.nlm.nih.gov/pubmed/16235327