Enhanced elimination

Haemodialysis can be considered in patients with severe kidney impairment (estimated glomerular filtration rate [eGFR] of less than 30 mL/minute) who present with severe toxicity (eg coma requiring intubation) from baclofen poisoningGhannoum 2021.

If haemodialysis is required, intermittent haemodialysis is the preferred modalityGhannoum 2021. For more information on haemodialysis, see Enhanced elimination of poisons.

If considering haemodialysis for baclofen poisoning, seek advice from a clinical toxicologist.