Second and subsequent recurrences of C. difficile infection in children younger than 18 years

For an overview of managing C. difficile infection in children, see Overview of managing a new episode of diarrhoea in children younger than 18 years with risk factors for Clostridioides difficile infection.

Seek expert advice for severe, complicated or fulminant disease (for definitions, see Severity assessment of C. difficile infection in children). For treatment recommendations, see Severe, complicated or fulminant Clostridioides difficile infection.

In children younger than 18 years with recurrent disease, investigate for other causes of diarrhoea because recurrence of C. difficile infection is uncommon in children. Seek expert advice for management of second and subsequent recurrences in children.