Clonidine for attention deficit hyperactivity disorder in children
Clonidine has a similar role to guanfacine for attention deficit hyperactivity disorder (ADHD) but its use is limited by its short half-life, which necessitates multiple-daily dosing. Clonidine does not appear to affect inattention symptoms and may cause depression; beneficial effects of clonidine may take several weeks to occur.
If clonidine is indicated for ADHD in children 6 years or older, a suitable regimen is:
clonidine 50 micrograms orally, daily. Increase the daily dose, according to response and tolerability, by no more than 50 micrograms (increase the dose or frequency of dosing) at intervals of 3 days, until optimal response is obtained or a daily dose of 300 micrograms (in up to 4 divided doses) is reached. Usual daily dose 3 to 5 micrograms/kg in divided doses. See further advice on monitoring and duration of treatment. attention deficit hyperactivity disorder clonidine